Washington Redskins vs. Buffalo Bills
- Robert Griffin III made his debut and worked the first quarter completing four of six passes for 70 yards and a touchdown.
- Pierre Garcon caught three passes for 58 yards and a score.
- Ryan Fitzpatrick and the first team offense didn't attempt a rush, but Fitz completed six-of-14 for 61 yards.
Baltimore Ravens vs. Atlanta Falcons
- It was a perfect start for Matt Ryan. Matty-ice completed his first six passes en route to an opening series touchdown to Julio Jones. (Ryan- 9/13 155 yards TD, INT)
- Jones caught six passes for 109 yards and the touchdown.
- Jazquizz Rodgers ran nine times for 33 yards and a score. He had three attempts at the stripe.
- Joe Flacco completed nine of 12 passes for 88 yards and a touchdown.
- Ray Rice ran three times for four yards.
New Orleans Saints vs. New England Patriots
- Drew Brees played two series and went one for four for only four yards.
- Tom Brady went four for seven for 30 yards.
- Shane Vereen ran the ball 11 times for 64 yards.
Pittsburgh Steelers vs. Philadelphia Eagles
- Ben Roethlisberger connected on seven of eight passes for 49 yards.
- Isaac Redman ran five times for 14 yards.
- Michael Vick completed three of four passes for six yards befor leaving the game after injuring his left thumb. X-rays were negative.
- LeSean McCoy had one carry and caught one pass for a total of -5 yards offense.
Green Bay Packers vs. San Diego Chargers
- Aaron Rodgers had a challenging start completing only two passes for 16 yards and one interception.
- Randall Cobb caught four passes for 58 yards and a touchdown.
- James Starks ran five times for 16 yards.
- Philip Rivers went three-for-five with 37 yards passing with a touchdown and an interception.
- Antonio Gates caught two passes for 29 yards and a touchdown.
Denver Broncos vs. Chicago Bears
- Peyton Manning returned for the first time in a Denver Broncos uniform after missing all of last season. Manning completed four-of-seven passes for 44 yards and threw one interception.
- Willis McGahee carried four times for 16 yards.